A large theme of his work is molecular topology, specifically mechanically-interlocked molecular architectures.
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Molecular Borromean rings are the molecular counterparts of Borromean rings, which are mechanically-interlocked molecular architectures.
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Stoddart has pioneered the use of mechanically interlocked molecular architectures to create top-down approach of lithography and microfabrication.
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The neuronal porosome proteome has been solved, providing the molecular architecture and the complete composition of the machinery.
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Tirrell and his co-workers have formed crystals, liquid crystals and gels with predetermined, programmable molecular architectures and accompanying properties.
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In 2012, two independent efforts have elucidated the molecular architecture of the 26S proteasome by single particle electron microscopy.
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The terminology " mechanical bond " has been coined to describe the connection between the components of mechanically interlocked molecular architectures.
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Stoddart has developed highly efficient syntheses of mechanically-interlocked molecular architectures such as molecular Borromean rings, catenanes and rotaxanes utilizing molecular recognition and molecular self-assembly processes.
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In particular they have been used to synthesize certain mechanically interlocked molecular architectures, such as rotaxanes and catenanes, by reacting the ends of the threaded guest.
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The discoveries of MAO and fluorinated aryl borate cocatalysts reenergized this field, leading to the promise of precise control of molecular architecture for these commercially important polymers.